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GLP-1 drugs work by slowing stomach emptying, increasing feelings of fullness and triggering the release of insulin

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The new trials also strengthen the evidence that GLP-1 weight loss requires continued use, which has been a source of criticism, even though continued use is normal for most other medications for chronic diseases

ATP measurements ATP measurements on GLUTag cells in response to 1 mM butyrate were performed in the same culture conditions as GLP-1 secretion assays, using Cell Titer Glow assay (Promega) according to the manufacturers protocol